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© 2026 cohaga AG · All Rights Reserved · St. Gallen, Switzerland · Imprint745,041 companies indexed · Last updated: today
DirectoryIndustryChemical IndustryPrattelnSynphaBase AG
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SynphaBase AG

Summary

About the company

The core activity of SynphaBase AG is the development and implementation of processes for the synthesis of complex organic compounds, particularly in the fields of medicinal chemistry, carbohydrate chemistry and process research and development. The company offers services such as laboratory synthesis, synthesis route development, process development and the production of organic and bioactive molecules.

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Industry:Chemical IndustryPharmaceutical Industry
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Contract synthesis of complex molecules
Contract synthesis of complex molecules from glycans, peptides, RNA and conjugates; route design, process optimization, material supply as well as scale-up and tech transfer.
Glycochemistry
Glycosylation and protecting-group strategies, modified sugars, oligosaccharides and glyco-conjugates as well as complex carbohydrate derivatives.
RNA and nucleotide building blocks
RNA building blocks and modified nucleotides, siRNA and oligonucleotide constructs as well as enzyme substrates and derivatives.
Peptides and amino acid derivatives
Non-natural amino acids, peptides and functionalized derivatives for demanding synthesis projects.
Conjugates and linker systems
Protein and antibody conjugation linkers, glyco-, peptido- and hybrid systems, as well as amphiphilic molecules.
Route design
Development of viable synthesis routes for challenging target molecules, strategies for complex molecules, removal of bottlenecks and early feasibility assessment.
Process optimization
Optimization of yield, selectivity and reproducibility, control of side reactions and impurities, and robust reaction and cleaning conditions.
Material supply
Manufacture and delivery of small quantities from developed processes, from milligram to multi-kilogram quantities, including reference materials and tech transfer support.
GMP manufacturing for early clinical supply
GMP-compliant manufacture of API material in multi-gram quantities for early clinical phases I/II under ICH Q7.
GMP laboratory infrastructure
Controlled synthesis, purification and final isolation in the GMP laboratory using chromatography, lyophilisation and compliant sampling procedures.
Regulatory oversight and inspection
Regular Swissmedic inspections, customer audits and documented compliance with regulatory requirements as well as data integrity.
Certified quality management system
ISO 9001-aligned, structured and traceable processes with ongoing monitoring across all projects.

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Location

Güterstrasse 82
4133 Pratteln
Opening hours
Mon
08:00 - 18:00
Tue
08:00 - 18:00
Wed
08:00 - 18:00
Thu
08:00 - 18:00
Fri
08:00 - 18:00
Sat
Closed
Sun
Closed

At a glance

Legal form
Corporation
UID
CHE-101.399.656
Founded
2000 · 26 years
Last commercial register change
April 23, 2026
Employees
11 to 20

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